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Multiple Choice

Which situation best describes the use of Yttrium-90 radioembolization?

Yttrium-90 radioembolization treats liver tumors by delivering targeted radiation from within the hepatic artery. It uses microspheres loaded with Y-90 that lodge in the tumor’s microvasculature, delivering a high radiation dose to the tumor while sparing most normal liver tissue. This makes it particularly suited for hepatocellular carcinoma that cannot be surgically removed, including cases with portal vein thrombosis, where other liver-directed therapies like TACE may be less safe or effective. It can also be used after TACE if residual disease remains or control is insufficient. It isn’t used for benign liver lesions or acute hepatic failure.

Yttrium-90 radioembolization treats liver tumors by delivering targeted radiation from within the hepatic artery. It uses microspheres loaded with Y-90 that lodge in the tumor’s microvasculature, delivering a high radiation dose to the tumor while sparing most normal liver tissue. This makes it particularly suited for hepatocellular carcinoma that cannot be surgically removed, including cases with portal vein thrombosis, where other liver-directed therapies like TACE may be less safe or effective. It can also be used after TACE if residual disease remains or control is insufficient. It isn’t used for benign liver lesions or acute hepatic failure.