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Multiple Choice

Which liver mass is the most common malignant mass?

Hepatocellular carcinoma is the liver’s most common primary malignant tumor. It typically arises in a liver already damaged by chronic disease, such as cirrhosis from hepatitis B or C, alcohol, or nonalcoholic fatty liver disease. Among the lesions listed, the others are benign: cavernous hemangioma is the most common benign liver tumor, focal nodular hyperplasia is a benign lesion often seen in young women, and hepatic adenoma is benign (though it can rupture or rarely transform). Therefore, the malignant mass that is most common is hepatocellular carcinoma. In imaging, HCC often shows arterial-phase enhancement with portal venous/delayed washout, and AFP may be elevated in many cases, supporting the diagnosis in the appropriate setting.

Hepatocellular carcinoma is the liver’s most common primary malignant tumor. It typically arises in a liver already damaged by chronic disease, such as cirrhosis from hepatitis B or C, alcohol, or nonalcoholic fatty liver disease. Among the lesions listed, the others are benign: cavernous hemangioma is the most common benign liver tumor, focal nodular hyperplasia is a benign lesion often seen in young women, and hepatic adenoma is benign (though it can rupture or rarely transform). Therefore, the malignant mass that is most common is hepatocellular carcinoma. In imaging, HCC often shows arterial-phase enhancement with portal venous/delayed washout, and AFP may be elevated in many cases, supporting the diagnosis in the appropriate setting.