Which is the most common cancer of the lymph nodes?

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Cancer that starts in the lymphatic tissue of the nodes is lymphoma. Lymph nodes are packed with lymphocytes, so when these immune cells become malignant, they form lymphoma, which is the most common cancer that originates in the lymph nodes. Leukemia arises from bone marrow and spills into blood; it can involve nodes but isn’t a cancer that begins in the nodes. Melanoma is skin cancer that may spread to nodes, not a primary lymph node cancer. Sarcoma comes from connective tissues and isn’t centered in lymph nodes. So lymphoma is the best answer because it specifically originates in lymphoid tissue within the nodes.