Which hormonal factor may influence growth of hepatic hemangiomas?

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Multiple Choice

Which hormonal factor may influence growth of hepatic hemangiomas?

Estrogen exposure is the hormonal factor most linked to growth of hepatic hemangiomas. These vascular tumors can enlarge when estrogen levels rise, such as during pregnancy or with estrogen-containing medications. Estrogen promotes angiogenesis and endothelial cell proliferation, which can expand the blood-filled channels of a hemangioma. Other hormones listed don’t have a clear, consistent effect on these lesions: progesterone isn’t reliably associated with growth, and androgen therapy or growth hormone are not typically implicated in driving hepatic hemangioma enlargement.

Estrogen exposure is the hormonal factor most linked to growth of hepatic hemangiomas. These vascular tumors can enlarge when estrogen levels rise, such as during pregnancy or with estrogen-containing medications. Estrogen promotes angiogenesis and endothelial cell proliferation, which can expand the blood-filled channels of a hemangioma. Other hormones listed don’t have a clear, consistent effect on these lesions: progesterone isn’t reliably associated with growth, and androgen therapy or growth hormone are not typically implicated in driving hepatic hemangioma enlargement.

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