Polycystic liver disease inheritance is which pattern?

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Multiple Choice

Polycystic liver disease inheritance is which pattern?

Autosomal dominant inheritance. Polycystic liver disease typically runs in families with vertical transmission, so a single mutated gene can pass the condition from one generation to the next. In practice, many cases show hepatic cysts as the main feature and may be due to dominant mutations (for example, in genes like PRKCSH or SEC63). While there is an autosomal recessive form and liver cysts can occur with autosomal dominant polycystic kidney disease, the pattern most commonly tested for polycystic liver disease itself is autosomal dominant. X-linked or mitochondrial patterns are not characteristic for this condition.

Autosomal dominant inheritance. Polycystic liver disease typically runs in families with vertical transmission, so a single mutated gene can pass the condition from one generation to the next. In practice, many cases show hepatic cysts as the main feature and may be due to dominant mutations (for example, in genes like PRKCSH or SEC63). While there is an autosomal recessive form and liver cysts can occur with autosomal dominant polycystic kidney disease, the pattern most commonly tested for polycystic liver disease itself is autosomal dominant. X-linked or mitochondrial patterns are not characteristic for this condition.

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